Buy Selank Online
Selank is a synthetic neuroactive peptide derived from the naturally occurring tuftsin peptide sequence. It has been researched primarily for anxiety-related pathways, stress responses, GABAergic signaling, and neurochemical regulation.
Selank has received particular attention in Russian clinical and experimental research as a peptide with anxiolytic and neuroregulatory properties.
Product Information
Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Research has investigated its influence on anxiety-related behavior, enkephalin metabolism, neurotransmission, and gene expression associated with GABAergic signaling.
A randomized clinical study involving 62 patients with generalized anxiety disorder and neurasthenia compared Selank with medazepam and reported similar anxiolytic effects, along with additional antiasthenic and psychostimulant effects.
How Does Selank Work?
Research suggests that Selank can influence GABAergic signaling and enkephalin metabolism, while experimental work has also identified changes in genes involved in neurotransmission.
Selank Benefits
Supports Anxiety Research:
Clinical research has investigated Selank in patients with generalized anxiety disorder and neurasthenia. In a randomized comparative study, the peptide produced anxiolytic effects comparable to medazepam on the study’s reported measures.
Influences GABAergic Signaling:
Animal research has shown that Selank changes the expression of multiple genes involved in GABAergic neurotransmission. The findings suggest that modulation of the GABA system may contribute to some of the peptide’s neurological effects.
Research Into Stress and Neurochemical Regulation:
Selank has also been investigated in relation to enkephalin metabolism. Experimental research found that Selank can inhibit enzymes involved in enkephalin degradation, providing another proposed mechanism for its anxiolytic activity.
Research Into Cognitive and Behavioral Function:
Because Selank influences several neurotransmission-related pathways rather than acting through a single conventional receptor target, it continues to be studied for broader effects on stress responses, behavior, and neurological function.
Selank Side Effects
Available clinical reports have generally described Selank as well tolerated, but modern independent safety data remain limited. The published evidence base is considerably smaller than that for established anxiolytic medications.
Selank Dosage
Published research has used different administration protocols.
Clinical research has investigated intranasal Selank formulations, while experimental animal research has used doses such as 300 μg/kg to investigate GABAergic gene-expression changes. The 300 μg/kg figure comes from a rat study and should not be interpreted as a human dose.
Because clinical publications have used different formulations and administration schedules, there is no single universally established dosing protocol that applies across all Selank preparations.
Research References
Zozulia AA, Neznamov GG, Siuniakov TS, et al. Efficacy and possible mechanisms of action of a new peptide anxiolytic Selank in the therapy of generalized anxiety disorders and neurasthenia. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(4):38–48. PMID: 18454096.
PubMed — Selank Clinical Anxiety Study
Volkova A, Shadrina M, Kolomin T, et al. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Frontiers in Pharmacology. 2016;7:31. PMID: 26924987.
PubMed — Selank GABAergic Research
Zozulya AA, Kost NV, Sokolov OYu, et al. The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity. PMID: 11550013.
PubMed — Selank Enkephalin Research
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The information provided in these pages is intended for educational and informational purposes only and should not be considered medical advice, diagnosis, or a recommendation to use any peptide. Research doses are included to describe published study protocols and are not individualized dosing instructions. Product quality, formulation, purity, route of administration, regulatory status, and availability may vary between suppliers and jurisdictions.
